Even when it becomes a non-fungible token, the artwork can still freely circulate over the internet, be seen, saved, sent or otherwise used. In buying an NFT, a user doesn’t just purchase the digital representation of the artwork, they’re buying the proof that the ownership rights belong exclusively to them (like the title deeds of a property). Ultimately, the buyer gets a high-resolution digital artwork file and a token that holds information on all the transactions associated with that artwork. Thus, the Contract Address for Beeple's CROSSROADS is 0x12f28e2106ce8fd8464885b80ea865e98b465149 and the Token ID is 100010001.
Digital artists can also create "shares" of their works - NFT fractions. This gives collectors and investors a chance to buy part of an NFT instead of paying millions to own the whole piece. Similarly, a creator can issue a collection of almost identical NFTs, much like collection cards but each would have its own unique identifier.